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Neutral DNA-avidin nanoparticles as ultrasensitive reporters in immuno-PCR

We have developed an immuno-PCR based diagnostic platform which couples detection antibodies to self-assembled, ultra-detectable DNA-avidin nanoparticles stabilized with poly(ethylene glycol) to link DNA amplification to target protein concentration. Electrostatic neutralization and cloaking of the...

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Detalles Bibliográficos
Publicado en:Analyst
Main Authors: Chavan, Dimple, Chen, Hui, Crum, Mary, Vu, Binh, Safari, Mohammad, Smith, Maxwell, Vekilov, Peter, Conrad, Jacinta C., Kourentzi, Katerina, Willson, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412439/
https://ncbi.nlm.nih.gov/pubmed/32500871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0an00134a
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