Neutral DNA-avidin nanoparticles as ultrasensitive reporters in immuno-PCR

We have developed an immuno-PCR based diagnostic platform which couples detection antibodies to self-assembled, ultra-detectable DNA-avidin nanoparticles stabilized with poly(ethylene glycol) to link DNA amplification to target protein concentration. Electrostatic neutralization and cloaking of the...

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Dettagli Bibliografici
Pubblicato in:Analyst
Autori principali: Chavan, Dimple, Chen, Hui, Crum, Mary, Vu, Binh, Safari, Mohammad, Smith, Maxwell, Vekilov, Peter, Conrad, Jacinta C., Kourentzi, Katerina, Willson, Richard C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412439/
https://ncbi.nlm.nih.gov/pubmed/32500871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0an00134a
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