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Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses

Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many bioinformatic tools on consensus sequence construction has precluded a thorough analysis of intra-host diversity. To take full advantage of the resoluti...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Gibson, Keylie M., Steiner, Margaret C., Rentia, Uzma, Bendall, Matthew L., Pérez-Losada, Marcos, Crandall, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412389/
https://ncbi.nlm.nih.gov/pubmed/32674515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12070758
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