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Design, Synthesis and Biological Evaluation of Novel Anthraniloyl-AMP Mimics as PQS Biosynthesis Inhibitors Against Pseudomonas aeruginosa Resistance

The Pseudomonas quinolone system (PQS) is one of the three major interconnected quorum sensing signaling systems in Pseudomonas aeruginosa. The virulence factors PQS and HHQ activate the transcription regulator PqsR (MvfR), which controls several activities in bacteria, including biofilm formation a...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Sabir, Shekh, Subramoni, Sujatha, Das, Theerthankar, Black, David StC., Rice, Scott A., Kumar, Naresh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412332/
https://ncbi.nlm.nih.gov/pubmed/32646050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25133103
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