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microRNA-99a Restricts Replication of Hepatitis C Virus by Targeting mTOR and De Novo Lipogenesis

In this study, we investigated the role of microRNA-99a (miR-99a) in hepatitis C virus (HCV) replication and lipogenesis in hepatocytes. Cell-culture-derived HCV (HCVcc) infection caused down-regulation of miR-99a in Huh-7 cells, and the relative levels of miR-99a were significantly lower in the ser...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Lee, Eun Byul, Sung, Pil Soo, Kim, Jung-Hee, Park, Dong Jun, Hur, Wonhee, Yoon, Seung Kew
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411587/
https://ncbi.nlm.nih.gov/pubmed/32605105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12070696
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