Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis

Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States. Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to synthesize collagen and extracellular matrix proteins. Although suppression of macrophage‐derived cytokine production...

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Pubblicato in:EMBO Mol Med
Autori principali: Zhang, Fenghua, Ayaub, Ehab A, Wang, Bingbing, Puchulu‐Campanella, Estela, Li, Yen‐Hsing, Hettiarachchi, Suraj U, Lindeman, Spencer D, Luo, Qian, Rout, Sasmita, Srinivasarao, Madduri, Cox, Abigail, Tsoyi, Konstantin, Nickerson‐Nutter, Cheryl, Rosas, Ivan O, Low, Philip S
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411553/
https://ncbi.nlm.nih.gov/pubmed/32597014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012034
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