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Suppression of sirtuin 1 alleviates airway inflammation through mTOR-mediated autophagy
Sirtuin 1 (SIRT1) is involved in the pathogenesis of allergic asthma. This study aimed to investigate whether EX-527, a specific SIRT1 inhibitor, exerted suppressive effects on allergic airway inflammation in mice submitted to ovalbumin (OVA) inhalation. In addition, this study assessed whether such...
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| 出版年: | Mol Med Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
D.A. Spandidos
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7411491/ https://ncbi.nlm.nih.gov/pubmed/32705226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11338 |
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