Wild-type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells

Glioblastoma (GBM) is the most common type of brain cancer and has the highest mortality. Dysregulated expression of wild-type isocitrate dehydrogenase 1 (IDH1) has been demonstrated to promote the progression of primary GBM without accumulating D-2-hydroxyglutarate, which differs from IDH1 mutation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Med Rep
Prif Awduron: Shen, Xiaopeng, Wu, Shen, Zhang, Jingyi, Li, Meng, Xu, Feng, Wang, Ao, Lei, Yang, Zhu, Guoping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2020
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411459/
https://ncbi.nlm.nih.gov/pubmed/32705169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11250
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