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Optimization of a Soft Ensemble Vote Classifier for the Prediction of Chimeric Virus-Like Particle Solubility and Other Biophysical Properties

Chimeric virus-like particles (cVLPs) are protein-based nanostructures applied as investigational vaccines against infectious diseases, cancer, and immunological disorders. Low solubility of cVLP vaccine candidates is a challenge that can prevent development of these very substances. Solubility of c...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Vormittag, Philipp, Klamp, Thorsten, Hubbuch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411134/
https://ncbi.nlm.nih.gov/pubmed/32850736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00881
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