AKT Inhibitor SC66 Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Through Down-Regulating AKT/β-Catenin Pathway

Glioblastoma multiforme (GBM) is the most common intracranial malignancy in adults with the highest degree of malignancy and mortality. Due to its nature of diffuse invasiveness and high migration, GBM lacks an effective treatment strategy and is associated with poor prognosis. SC66 is a novel AKT i...

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Publicado no:Front Pharmacol
Main Authors: Gao, Lun, Liu, Junhui, Xu, Pengfei, Deng, Gang, Liu, Baohui, Yuan, Fanen, Tan, Yinqiu, Sun, Qian, Xu, Yang, Zhang, Huikai, Qi, Yangzhi, Han, Shoumeng, Yang, Kun, Geng, Rongxin, Jiang, Hongxiang, Chen, Qianxue
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411127/
https://ncbi.nlm.nih.gov/pubmed/32848734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01102
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