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Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy in highly malignant brain-tumors, glioblastomas (GBM), is limited. Here, we generate distinct imageable syngeneic mouse GBM-tumor models and utilize RNA-sequencing, CyTOF and correlative immunohistochemistry to...

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書誌詳細
出版年:Nat Commun
主要な著者: Khalsa, Jasneet Kaur, Cheng, Nina, Keegan, Joshua, Chaudry, Ameen, Driver, Joseph, Bi, Wenya Linda, Lederer, James, Shah, Khalid
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411074/
https://ncbi.nlm.nih.gov/pubmed/32764562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17704-5
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