Syndecan-4(–/–) Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components

BACKGROUND: Extracellular matrix (ECM) remodeling is essential for skeletal muscle development and adaption in response to environmental cues such as exercise and injury. The cell surface proteoglycan syndecan-4 has been reported to be essential for muscle differentiation, but few molecular mechanis...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Rønning, Sissel Beate, Carlson, Cathrine Rein, Aronsen, Jan Magnus, Pisconti, Addolorata, Høst, Vibeke, Lunde, Marianne, Liland, Kristian Hovde, Sjaastad, Ivar, Kolset, Svein Olav, Christensen, Geir, Pedersen, Mona Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411008/
https://ncbi.nlm.nih.gov/pubmed/32850844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00730
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