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An extended and generalized framework for the calculation of metabolic intervention strategies based on minimal cut sets

The concept of minimal cut sets (MCS) provides a flexible framework for analyzing properties of metabolic networks and for computing metabolic intervention strategies. In particular, it has been used to support the targeted design of microbial strains for bio-based production processes. Herein we pr...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Schneider, Philipp, von Kamp, Axel, Klamt, Steffen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410339/
https://ncbi.nlm.nih.gov/pubmed/32716928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008110
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