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Speeding up the core algorithm for the dual calculation of minimal cut sets in large metabolic networks

BACKGROUND: The concept of minimal cut sets (MCS) has become an important mathematical framework for analyzing and (re)designing metabolic networks. However, the calculation of MCS in genome-scale metabolic models is a complex computational problem. The development of duality-based algorithms in the...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Klamt, Steffen, Mahadevan, Radhakrishnan, von Kamp, Axel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654042/
https://ncbi.nlm.nih.gov/pubmed/33167871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03837-3
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