Gene expression regulated by abatacept associated with methotrexate and correlation with disease activity in rheumatoid arthritis

OBJECTIVES: Abatacept acts as a competitive inhibitor of the CD28/(CD80/86) costimulation signal required for T cell activation. Mechanisms of action of abatacept have not been fully investigated. The objective of this study was to provide detailed insight into the mode of action of Abatacept based...

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Udgivet i:PLoS One
Main Authors: Derambure, Céline, Dzangue-Tchoupou, Gaelle, D’Agostino, Maria Antonietta, Lequerré, Thierry, Vittecoq, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410313/
https://ncbi.nlm.nih.gov/pubmed/32760165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237143
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