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Gene expression regulated by abatacept associated with methotrexate and correlation with disease activity in rheumatoid arthritis

OBJECTIVES: Abatacept acts as a competitive inhibitor of the CD28/(CD80/86) costimulation signal required for T cell activation. Mechanisms of action of abatacept have not been fully investigated. The objective of this study was to provide detailed insight into the mode of action of Abatacept based...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Derambure, Céline, Dzangue-Tchoupou, Gaelle, D’Agostino, Maria Antonietta, Lequerré, Thierry, Vittecoq, Olivier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410313/
https://ncbi.nlm.nih.gov/pubmed/32760165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237143
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