AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes

Type 2 diabetes is clinically associated with progressive necroinflammation and fibrosis in nonalcoholic steatohepatitis (NASH). Advanced glycation end-products (AGEs) accumulate during prolonged hyperglycemia, but the mechanistic pathways that lead to accelerated liver fibrosis have not been well d...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Dehnad, Ali, Fan, Weiguo, Jiang, Joy X., Fish, Sarah R., Li, Yuan, Das, Suvarthi, Mozes, Gergely, Wong, Kimberly A., Olson, Kristin A., Charville, Gregory W., Ali, Mohammed, Török, Natalie J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410084/
https://ncbi.nlm.nih.gov/pubmed/32657776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133051
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