Autoantibodies targeting TRIM72 compromise membrane repair and contribute to inflammatory myopathy

Idiopathic inflammatory myopathies (IIM) involve chronic inflammation of skeletal muscle and subsequent muscle degeneration due to an uncontrolled autoimmune response; however, the mechanisms leading to pathogenesis are not well understood. A compromised sarcolemmal repair process could promote an a...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: McElhanon, Kevin E., Young, Nicholas, Hampton, Jeffrey, Paleo, Brian J., Kwiatkowski, Thomas A., Beck, Eric X, Capati, Ana, Jablonski, Kyle, Gurney, Travis, Perez, Miguel A. Lopez, Aggarwal, Rohit, Oddis, Chester V., Jarjour, Wael N., Weisleder, Noah
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410050/
https://ncbi.nlm.nih.gov/pubmed/32687067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131721
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