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Kinetic Heterogeneity of Cancer Cell Fractional Killing

Lethal drugs can induce incomplete cell death in a population of cancer cells, a phenomenon referred to as fractional killing. Here, we show that high-throughput population-level time-lapse imaging can be used to quantify fractional killing in response to hundreds of different drug treatments in par...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Inde, Zintis, Forcina, Giovanni C., Denton, Kyle, Dixon, Scott J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409774/
https://ncbi.nlm.nih.gov/pubmed/32640215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107845
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