Expression and clinical significance of LAG-3, FGL1, PD-L1 and CD8(+)T cells in hepatocellular carcinoma using multiplex quantitative analysis

BACKGROUND: Fibrinogen-like protein 1 (FGL1)—Lymphocyte activating gene 3 (LAG-3) pathway is a promising immunotherapeutic target and has synergistic effect with programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1). However, the prognostic significance of FGL1-LAG-3 pathway and the correlatio...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Guo, Mengzhou, Yuan, Feifei, Qi, Feng, Sun, Jialei, Rao, Qianwen, Zhao, Zhiying, Huang, Peixin, Fang, Tingting, Yang, Biwei, Xia, Jinglin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409704/
https://ncbi.nlm.nih.gov/pubmed/32762721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02469-8
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