tRNA(Arg)-derived fragments can serve as arginine donors for protein arginylation.

Arginyltransferase ATE1 mediates posttranslational arginylation and plays key roles in multiple physiological processes. ATE1 utilizes arginyl (Arg)-tRNA(Arg) as the donor of Arg, putting this reaction into a direct competition with the protein synthesis machinery. Here, we address the question of A...

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Udgivet i:Cell Chem Biol
Main Authors: Avcilar-Kucukgoze, Irem, Gamper, Howard, Polte, Christine, Ignatova, Zoya, Kraetzner, Ralph, Shtutman, Michael, Hou, Ya-Ming, Dong, Dawei W., Kashina, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409373/
https://ncbi.nlm.nih.gov/pubmed/32553119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.05.013
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