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Dual-Agent Photodynamic Therapy with Optical Clearing Eradicates Pigmented Melanoma in Preclinical Tumor Models

Treatment using light-activated photosensitizers (photodynamic therapy, PDT) has shown limited efficacy in pigmented melanoma, mainly due to the poor penetration of light in this tissue. Here, an optical clearing agent (OCA) was applied topically to a cutaneous melanoma model in mice shortly before...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pires, Layla, Demidov, Valentin, Wilson, Brian C., Salvio, Ana Gabriela, Moriyama, Lilian, Bagnato, Vanderlei S., Vitkin, I. Alex, Kurachi, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409296/
https://ncbi.nlm.nih.gov/pubmed/32708501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071956
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