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High efficiency of benzoporphyrin derivative in the photodynamic therapy of pigmented malignant melanoma

Benzoporphyrin derivative monoacid ring A (verteporfin, BPD-MA) when intravenously injected (5.5 μmol kg(−1)) to C57/BL6 mice bearing a subcutaneously transplanted B1 melanoma gave a maximal accumulation in the tumour within 1–3 h with recoveries of 1.84– 1.96 μmol kg(−1). Irradiation of BPD-MA-load...

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Detalhes bibliográficos
Main Authors: Busetti, A, Soncin, M, Jori, G, Rodgers, M A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362652/
https://ncbi.nlm.nih.gov/pubmed/10070875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690131
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