Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-κB Activation in Oral Cancer Cells

A subset of oral carcinomas is etiologically related to high-risk human papillomavirus (HR-HPV) infection, with HPV16 being the most frequent HR-HPV type found in these carcinomas. The oncogenic role of HR-HPV is strongly dependent on the overexpression of E6 and E7 oncoproteins, which, in turn, ind...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Carrillo-Beltrán, Diego, Muñoz, Juan P., Guerrero-Vásquez, Nahir, Blanco, Rancés, León, Oscar, de Souza Lino, Vanesca, Tapia, Julio C., Maldonado, Edio, Dubois-Camacho, Karen, Hermoso, Marcela A., Corvalán, Alejandro H., Calaf, Gloria M., Boccardo, Enrique, Aguayo, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409273/
https://ncbi.nlm.nih.gov/pubmed/32679705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071904
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