Microbial Natural Products as Potential Inhibitors of SARS-CoV-2 Main Protease (M(pro))

The main protease (M(pro)) of the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was subjected to hyphenated pharmacophoric-based and structural-based virtual screenings using a library of microbial natural products (>24,000 compounds). Subsequent filtering of the resu...

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Veröffentlicht in:Microorganisms
Hauptverfasser: Sayed, Ahmed M., Alhadrami, Hani A., El-Gendy, Ahmed O., Shamikh, Yara I., Belbahri, Lassaad, Hassan, Hossam M., Abdelmohsen, Usama Ramadan, Rateb, Mostafa E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409236/
https://ncbi.nlm.nih.gov/pubmed/32610445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8070970
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