Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia

Natural killer (NK) cells are key cytotoxic effectors against malignant cells. Polygenic and polymorphic Killer cell Immunoglobulin-like Receptor (KIR) and HLA genes participate in the structural and functional formation of the NK cell repertoire. In this study, we extensively investigated the anti-...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Makanga, Dhon Roméo, Da Rin de Lorenzo, Francesca, David, Gaëlle, Willem, Catherine, Dubreuil, Léa, Legrand, Nolwenn, Guillaume, Thierry, Peterlin, Pierre, Lebourgeois, Amandine, Béné, Marie Christine, Garnier, Alice, Chevallier, Patrice, Gendzekhadze, Ketevan, Cesbron, Anne, Gagne, Katia, Clemenceau, Béatrice, Retière, Christelle
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409189/
https://ncbi.nlm.nih.gov/pubmed/32708751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071927
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