Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia

Natural killer (NK) cells are key cytotoxic effectors against malignant cells. Polygenic and polymorphic Killer cell Immunoglobulin-like Receptor (KIR) and HLA genes participate in the structural and functional formation of the NK cell repertoire. In this study, we extensively investigated the anti-...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Makanga, Dhon Roméo, Da Rin de Lorenzo, Francesca, David, Gaëlle, Willem, Catherine, Dubreuil, Léa, Legrand, Nolwenn, Guillaume, Thierry, Peterlin, Pierre, Lebourgeois, Amandine, Béné, Marie Christine, Garnier, Alice, Chevallier, Patrice, Gendzekhadze, Ketevan, Cesbron, Anne, Gagne, Katia, Clemenceau, Béatrice, Retière, Christelle
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409189/
https://ncbi.nlm.nih.gov/pubmed/32708751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071927
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