Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential

Telomeres are the ends of linear chromosomes comprised of repetitive nucleotide sequences in humans. Telomeres preserve chromosomal stability and genomic integrity. Telomere length shortens with every cell division in somatic cells, eventually resulting in replicative senescence once telomere length...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Fernandes, Stina George, Dsouza, Rebecca, Pandya, Gouri, Kirtonia, Anuradha, Tergaonkar, Vinay, Lee, Sook Y., Garg, Manoj, Khattar, Ekta
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409176/
https://ncbi.nlm.nih.gov/pubmed/32674474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071901
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