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Characterisation of Ovarian Cancer Cell Line NIH-OVCAR3 and Implications of Genomic, Transcriptomic, Proteomic and Functional DNA Damage Response Biomarkers for Therapeutic Targeting

In order to be effective models to identify biomarkers of chemotherapy response, cancer cell lines require thorough characterization. In this study, we characterised the widely used high grade serous ovarian cancer (HGSOC) cell line NIH-OVCAR3 using bioinformatics, cytotoxicity assays and molecular/...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Bradbury, Alice, O’Donnell, Rachel, Drew, Yvette, Curtin, Nicola J., Sharma Saha, Sweta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409137/
https://ncbi.nlm.nih.gov/pubmed/32709004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071939
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