Sjögren’s Syndrome Minor Salivary Gland CD4(+) Memory T Cells Associate with Glandular Disease Features and Have a Germinal Center T Follicular Helper Transcriptional Profile

To assess the types of salivary gland (SG) T cells contributing to Sjögren’s syndrome (SS), we evaluated SG T cell subtypes for association with disease features and compared the SG CD4(+) memory T cell transcriptomes of subjects with either primary SS (pSS) or non-SS sicca (nSS). SG biopsies were e...

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Опубликовано в: :J Clin Med
Главные авторы: Joachims, Michelle L., Leehan, Kerry M., Dozmorov, Mikhail G., Georgescu, Constantin, Pan, Zijian, Lawrence, Christina, Marlin, M. Caleb, Macwana, Susan, Rasmussen, Astrid, Radfar, Lida, Lewis, David M., Stone, Donald U., Grundahl, Kiely, Scofield, R. Hal, Lessard, Christopher J., Wren, Jonathan D., Thompson, Linda F., Guthridge, Joel M., Sivils, Kathy L., Moore, Jacen S., Farris, A. Darise
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408878/
https://ncbi.nlm.nih.gov/pubmed/32650575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9072164
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