Sjögren’s Syndrome Minor Salivary Gland CD4(+) Memory T Cells Associate with Glandular Disease Features and Have a Germinal Center T Follicular Helper Transcriptional Profile

To assess the types of salivary gland (SG) T cells contributing to Sjögren’s syndrome (SS), we evaluated SG T cell subtypes for association with disease features and compared the SG CD4(+) memory T cell transcriptomes of subjects with either primary SS (pSS) or non-SS sicca (nSS). SG biopsies were e...

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Publicado en:J Clin Med
Main Authors: Joachims, Michelle L., Leehan, Kerry M., Dozmorov, Mikhail G., Georgescu, Constantin, Pan, Zijian, Lawrence, Christina, Marlin, M. Caleb, Macwana, Susan, Rasmussen, Astrid, Radfar, Lida, Lewis, David M., Stone, Donald U., Grundahl, Kiely, Scofield, R. Hal, Lessard, Christopher J., Wren, Jonathan D., Thompson, Linda F., Guthridge, Joel M., Sivils, Kathy L., Moore, Jacen S., Farris, A. Darise
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408878/
https://ncbi.nlm.nih.gov/pubmed/32650575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9072164
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