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Advancements in PARP1 Targeted Nuclear Imaging and Theranostic Probes

The central paradigm of novel therapeutic approaches in cancer therapy is identifying and targeting molecular biomarkers. One such target is the nuclear DNA repair enzyme Poly-(ADP ribose) polymerase 1 (PARP1). Sensitivity to PARP inhibition in certain cancers such as gBRCA(mut) breast and ovarian c...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Ambur Sankaranarayanan, Ramya, Kossatz, Susanne, Weber, Wolfgang, Beheshti, Mohsen, Morgenroth, Agnieszka, Mottaghy, Felix M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408801/
https://ncbi.nlm.nih.gov/pubmed/32640708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9072130
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