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Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility

UreG is a P-loop GTP hydrolase involved in the maturation of nickel-containing urease, an essential enzyme found in plants, fungi, bacteria, and archaea. This protein couples the hydrolysis of GTP to the delivery of Ni(II) into the active site of apo-urease, interacting with other urease chaperones...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Pierro, Annalisa, Etienne, Emilien, Gerbaud, Guillaume, Guigliarelli, Bruno, Ciurli, Stefano, Belle, Valérie, Zambelli, Barbara, Mileo, Elisabetta
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408563/
https://ncbi.nlm.nih.gov/pubmed/32708696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10071062
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