Soluble CD14 Induces Pro-inflammatory Cytokines in Rheumatoid Arthritis Fibroblast-Like Synovial Cells via Toll-Like Receptor 4

Objectives: Synovial fluids of rheumatoid arthritis (RA) patients commonly contain high concentrations of soluble CD14 (sCD14). To investigate its potential role in RA pathogenesis, we tested whether sCD14 binding transmits a signal to fibroblast-like synoviocytes from RA patients (RA-FLS). Methods:...

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Publicado no:Cells
Main Authors: Ichise, Yoshihide, Saegusa, Jun, Tanaka-Natsui, Shino, Naka, Ikuko, Hayashi, Shinya, Kuroda, Ryosuke, Morinobu, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408546/
https://ncbi.nlm.nih.gov/pubmed/32674360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071689
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