Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts

INTRODUCTION: Toll-like receptors (TLRs) are likely to play crucial roles in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to determine the key TLRs in synovium and explore their roles in the activation of fibroblast-like synoviocytes (FLSs) mediated by T cells in arthriti...

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Bibliographic Details
Main Authors: Zhu, Wenhua, Meng, Liesu, Jiang, Congshan, He, Xiaojing, Hou, Weikun, Xu, Peng, Du, Heng, Holmdahl, Rikard, Lu, Shemin
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218918/
https://ncbi.nlm.nih.gov/pubmed/21708001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3384
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