MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis

OBJECTIVES: Mounting evidence has demonstrated that microRNAs (miRNAs) participate in rheumatoid arthritis (RA). The role of highly conserved miR-15/107 family in RA has not been clarified yet, and hence investigated in this study. METHODS: Reverse transcription-quantitative polymerase chain reactio...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wang, Si, Xu, Jing, Guo, Yuanxu, Cai, Yongsong, Ren, Xiaoyu, Zhu, Wenhua, Geng, Manman, Meng, Liesu, Jiang, Congshan, Lu, Shemin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034293/
https://ncbi.nlm.nih.gov/pubmed/33841401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.619392
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