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Improvement in the Oral Bioavailability and Efficacy of New Ezetimibe Formulations—Comparative Study of a Solid Dispersion and Different Micellar Systems

Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the highest oral bioavailability, and to improve their lipid-lowering effect. The...

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Publicat a:Pharmaceutics
Autors principals: Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Gallego-Arranz, Teresa, del Val-Sabugo, Yvonne, Torrado, Guillermo, Morales, Javier, Torrado-Santiago, Santiago
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408513/
https://ncbi.nlm.nih.gov/pubmed/32630626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070617
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