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Self-Micellizing Technology Improves the Properties of Ezetimibe and Increases Its Effect on Hyperlipidemic Rats

The aim of this work was to develop ezetimibe self-micellizing solid dispersions using Kolliphor(®) RH40 (MS-K) as a surfactant incorporating ezetimibe (EZ) into the croscarmellose hydrophilic carrier. Different ezetimibe:Kolliphor(®) ratios were studied to select micellar systems that improve the d...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Cerezo-Garreta, Javier, Torrado Durán, Guillermo, Torrado-Santiago, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956093/
https://ncbi.nlm.nih.gov/pubmed/31817021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11120647
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