Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs

Drug dosing in neonates should be based on integrated knowledge concerning the disease to be treated, the physiological characteristics of the neonate, and the pharmacokinetics (PK) and pharmacodynamics (PD) of a given drug. It is critically important that all sources of information be leveraged to...

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Udgivet i:Pharmaceutics
Main Authors: Van den Anker, John N., McCune, Susan, Annaert, Pieter, Baer, Gerri R., Mulugeta, Yeruk, Abdelrahman, Ramy, Wu, Kunyi, Krudys, Kevin M., Fisher, Jeffrey, Slikker, William, Chen, Connie, Burckart, Gilbert J., Allegaert, Karel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408157/
https://ncbi.nlm.nih.gov/pubmed/32698409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070685
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