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Clinical pharmacology in neonates: small size, huge variability

Drug therapy is a powerful tool to improve neonatal outcome. Despite this, neonatologists still routinely prescribe off label compounds developed for adults, and extrapolate doses from those used in children or adults. Knowledge integration through pharmacokinetic (PK) modeling is an important metho...

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Detalhes bibliográficos
Main Authors: Allegaert, Karel, van den Anker, John N
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111147/
https://ncbi.nlm.nih.gov/pubmed/24931327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000360648
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