Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

Inflammation is involved in the pathogenesis of several age-related ocular diseases, such as macular degeneration (AMD), diabetic retinopathy, and glaucoma. The delivery of anti-inflammatory siRNA to the retinal pigment epithelium (RPE) may become a promising therapeutic option for the treatment of...

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Udgivet i:Pharmaceutics
Main Authors: Ramsay, Eva, Raviña, Manuela, Sarkhel, Sanjay, Hehir, Sarah, Cameron, Neil R., Ilmarinen, Tanja, Skottman, Heli, Kjems, Jørgen, Urtti, Arto, Ruponen, Marika, Subrizi, Astrid
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407886/
https://ncbi.nlm.nih.gov/pubmed/32708811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070667
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