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Neural retina limits the nonviral gene transfer to retinal pigment epithelium in an in vitro bovine eye model

We investigated the permeation of liposomal and polymeric gene delivery systems through neural retina into retinal pigment epithelium (RPE) and determined the roles of various factors in permeation and subsequent uptake of the delivery systems by RPE. Anterior parts and vitreous of fresh bovine eyes...

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Detalhes bibliográficos
Main Authors: Pitkänen, Leena, Pelkonen, Jukka, Ruponen, Marika, Rönkkö, Seppo, Urtti, Arto
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751250/
https://ncbi.nlm.nih.gov/pubmed/15760110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj060325
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