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Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations
SUMMARY STATEMENT: Pathogenic LRRK2 expression causes endolysosomal trafficking alterations by impairing RAB10 function, and these alterations are rescued by RAB29 independent of its Golgi localization. ABSTRACT: Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) cause familial Park...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7407826/ https://ncbi.nlm.nih.gov/pubmed/32709066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071719 |
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