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Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops(®) High Dose Dry Powder Inhalation Device While Maintaining Dispersibility

In recent years there has been increasing interest in the pulmonary delivery of high dose dry powder drugs, such as antibiotics. Drugs in this class need to be dosed in doses far over 2.5 mg, and the use of excipients should therefore be minimized. To our knowledge, the effect of the automatic filli...

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Опубликовано в: :Pharmaceutics
Главные авторы: Sibum, Imco, Hagedoorn, Paul, Botterman, Carel O., Frijlink, Henderik W., Grasmeijer, Floris
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407802/
https://ncbi.nlm.nih.gov/pubmed/32659899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070645
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