The Phytochemical Indicaxanthin Synergistically Enhances Cisplatin-Induced Apoptosis in HeLa Cells via Oxidative Stress-Dependent p53/p21(waf1) Axis

Combining phytochemicals with chemotherapics is an emerging strategy to treat cancer to overcome drug toxicity and resistance with natural compounds. We assessed the effects of indicaxanthin (Ind), a pigment obtained from Opuntia ficus-indica (L. Mill) fruit, combined with cisplatin (CDDP) against c...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Allegra, Mario, D’Anneo, Antonella, Frazzitta, Anna, Restivo, Ignazio, Livrea, Maria Antonia, Attanzio, Alessandro, Tesoriere, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407573/
https://ncbi.nlm.nih.gov/pubmed/32630700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10070994
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