Endothelial Cell Targeting by cRGD-Functionalized Polymeric Nanoparticles under Static and Flow Conditions

Since α(v)β(3) integrin is a key component of angiogenesis in health and disease, Arg-Gly-Asp (RGD) peptide-functionalized nanocarriers have been investigated as vehicles for targeted delivery of drugs to the α(v)β(3) integrin-overexpressing neovasculature of tumors. In this work, PEGylated nanopart...

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Udgivet i:Nanomaterials (Basel)
Main Authors: Martínez-Jothar, Lucía, Barendrecht, Arjan D., de Graaff, Anko M., Oliveira, Sabrina, van Nostrum, Cornelus F., Schiffelers, Raymond M., Hennink, Wim E., Fens, Marcel H. A. M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407316/
https://ncbi.nlm.nih.gov/pubmed/32664364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10071353
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