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Inhibition of Ligand-Gated TRPA1 by General Anesthetics

Several general anesthetics (GAs) produce pain or irritation upon administration, and this occurs predominantly through the activation of the nociceptive ion channel, transient receptor potential ankyrin type 1 (TRPA1). However, the effects of GAs on agonist-mediated TRPA1 activity are unclear. Here...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Ton, Hoai T., Phan, Thieu X., Ahern, Gerard P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406985/
https://ncbi.nlm.nih.gov/pubmed/32580996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.118851
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