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Loss of histone H4 lysine 20 trimethylation in osteosarcoma is associated with aberrant expression ofhistone methyltransferase SUV420H2

Epigenetic modifications of histones have crucial roles in various types of cancers. The aberrant trimethylation of histone H4 at lysine 20 (H4K20) has been implicated in carcinogenesis. At present, the status of trimethylation at H4k20 (H4K20me3) in osteosarcoma (OS), the predominant bone cancer in...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Piao, Lianhua, Yuan, Xiaofeng, Wang, Luhui, Xu, Xiaoshuang, Zhuang, Ming, Li, Jinggao, Kong, Ren, Liu, Zhiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406877/
https://ncbi.nlm.nih.gov/pubmed/32774499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11887
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