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Loss of histone H4 lysine 20 trimethylation in osteosarcoma is associated with aberrant expression ofhistone methyltransferase SUV420H2

Epigenetic modifications of histones have crucial roles in various types of cancers. The aberrant trimethylation of histone H4 at lysine 20 (H4K20) has been implicated in carcinogenesis. At present, the status of trimethylation at H4k20 (H4K20me3) in osteosarcoma (OS), the predominant bone cancer in...

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Bibliografiset tiedot
Julkaisussa:Oncol Lett
Päätekijät: Piao, Lianhua, Yuan, Xiaofeng, Wang, Luhui, Xu, Xiaoshuang, Zhuang, Ming, Li, Jinggao, Kong, Ren, Liu, Zhiwei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406877/
https://ncbi.nlm.nih.gov/pubmed/32774499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11887
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