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Autophagy in Chronic Myeloid Leukaemia: Stem Cell Survival and Implication in Therapy

The insensitivity of Chronic Myeloid Leukaemia (CML) stem cells to Tyrosine Kinase Inhibitor (TKI) treatment is now believed to be the main reason for disease persistence experienced in patients. It has been shown that autophagy, an evolutionarily conserved catabolic process that involves degradatio...

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Detalhes bibliográficos
Publicado no:Curr Cancer Drug Targets
Main Authors: Helgason, G. Vignir, Mukhopadhyay, Arunima, Karvela, Maria, Salomoni, Paolo, Calabretta, Bruno, Holyoake, Tessa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406427/
https://ncbi.nlm.nih.gov/pubmed/23941517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/15680096113139990088
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