Dietary Amino Acids Impact LRRK2-Induced Neurodegeneration in Parkinson's Disease Models

The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) is a common cause of Parkinson's disease (PD) and results in age-related dopamine neuron loss and locomotor dysfunction in Drosophila melanogaster through an aberrant increase in bulk neuronal protein synthesis. Under nonpathologic con...

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Publicat a:J Neurosci
Autors principals: Chittoor-Vinod, Vinita G., Villalobos-Cantor, Steffany, Roshak, Hanna, Shea, Kelsey, Abalde-Atristain, Leire, Martin, Ian
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406281/
https://ncbi.nlm.nih.gov/pubmed/32605938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2809-19.2020
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