Plasma cell-free DNA predicts pediatric cerebral malaria severity

BACKGROUND: Prediction of adverse outcomes in cerebral malaria (CM) is difficult. We hypothesized that cell-free DNA (cfDNA) levels would facilitate identification of severe and potentially fatal CM cases. METHODS: In this retrospective study, plasma from Malawian children with CM (n = 134), uncompl...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Vera, Iset Medina, Kessler, Anne, Ting, Li-Min, Harawa, Visopo, Keller, Thomas, Allen, Dylan, Njie, Madi, Moss, McKenze, Soko, Monica, Ahmadu, Ajisa, Kadwala, Innocent, Ray, Stephen, Nyirenda, Tonney S., Mandala, Wilson L., Taylor, Terrie E., Rogerson, Stephen J., Seydel, Karl B., Kim, Kami
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406267/
https://ncbi.nlm.nih.gov/pubmed/32554925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136279
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